Sr. Scientist / Principle Scientist, Antibody Engineering

Full Time
Boston, MA


We are seeking a highly motivated and experienced scientist in antibody engineering and protein modeling to join our antibody engineering team for antibody based therapeutic candidates development. A successful candidate should also have a thorough knowledge of principles of antibody engineering and have hands on experience in antibody molecular biology. S/he also will be leading the antibody engineering, humanization and affinity maturation projects and closely working with experienced scientists in a dynamic, fast-paced and highly collaborative environment.


  • Antibody, Fc fusion protein, multi-specific antibody engineering
  • Implement humanization and affinity maturation strategies and conduction
  • Determination of kinetic constants, and epitope mapping
  • Serve as a technical lead on projects in a cross-functional team setting and act as a champion for the antibody development
  • Take active role in coaching and mentoring the junior team members.


  • PhD is required in immunology, molecular biology, oncology, pharmacology or related life sciences
  • At least 5-10 years’ industry experience or equivalent in academia in antibody engineering
  • Proven track record of scientific accomplishments demonstrated by publications in high-impact journals, or successful experiences in Bio-pharm industry
  • Experience working with antibody/fusion protein large molecules drug development
  • Expertise in humanization, affinity maturation, and reformatting of antibodies
  • Strong interpersonal and management skills,
  • Good skills in written and oral communication, organization and multitasking, and working in a highly collaborative and cross-functional research environment
  • Excellent team player and leadership skill , highly reliable and responsible.

Job Type: Full-time

Required education:

  • Doctorate

Required experience:

antibody engineering: 4 years


We offer competitive compensation package, for additional information, please contact: